Please consult the OPDIVO Product Monograph or click here for important information relating to:

• The most serious warnings and precautions regarding severe/fatal immune-mediated adverse reactions (imARs), allogeneic hematopoietic stem cell transplantation (HSCT), multiple myeloma and administration under the supervision of physicians experienced in the treatment of cancer.

• Other relevant warnings and precautions regarding frequency and signs and symptoms of imARs, infusion reaction, patients on controlled sodium diet, caution when driving or operating a vehicle or potentially dangerous machinery, haemophagocytic lymphohistiocytosis (HLH), pregnancy, nursing and patients with moderate or severe hepatic or severe renal impairment.

• Conditions of clinical use, adverse reactions, drug interactions, and dosing instructions.

The Product Monograph is also available by calling us at: 1-866-463-6267.